Resume : The Sixth Gun takes place in the old west, shortly after the end of the Civil War. The story centers around a set of six pistols, each imbued with dark powers. The wielder of each pistol gains an ability unique to that weapon, and is tied to the pistol until his or her death. The guns are numbered, with the titular Sixth Gun belonging to one of the story's protagonists: Drake Sinclair, a gunfighter with a very pragmatic outlook on the guns. The other main protagonist is Becky Montcrief. The villains of the series include recurring antagonist General Hume, the Knights of Solomon, the Sword of Abraham, and others vying for control of the guns.